Researchers are invited to make use of the assays detailed below. In case of any technical query, the scientists concerned may be approached through email

Model/Assay	Assay System	Disease area
Sander-Cramer assay for evaluation of spermicidal activity	In vitro	Contraception
Assay for vaginal contraception in Rabbit	In vivo	Contraception
Anti-implantation assay for the contraceptive agent development	In vivo	Reproductive Health Research
Hyperandrogenized polycystic ovary syndrome (PCOS) assay	In vivo	Reproductive Health Research
Granulosa cells steroidogenesis assay	In vivo	Reproductive Health Research
Autologous/ heterologous Endometriosis assay	In vivo	Reproductive Health Research
Evaluation of Anti-proliferative activity against human BPH-stromal primary cells	In vitro	Benign Prostatic Hyperplasia
In vivo assay for anti-BPH activity in rat model	In vivo	Benign Prostatic Hyperplasia
Anti-spermatogenic activity in rats	In vivo	Contraception
Wound healing assay	In vitro
Migration and invasion assays	In vitro	Cancer
DMBA-induced mammary tumor model	In vivo	Breast cancer
Topoisomerase inhibition assay	In vitro	Cancer
Anti-proliferation Assay in Primary cell lines	In vitro screening for the compounds anti-proliferation activity	Cancer
Apoptosis assay in primary cells/ tumors -To evaluate the anti-cancerous properties of a particular compound using apoptosis assay	In vitro/ In vivo	Cancer
DNMT, HDAC, HAT activity assays - Epigenetic assays for aging and anti-cancer research. Assays being used to evaluate the epigenetic targets of novel compounds in mammalian cell lines. The major epigenetic targets are DNMTs, HATs and HDACs.	In vitro
Telomerase assay	In vitro	Cancer, Aging
Chromatin Immuno Precipitation (ChIP) assay- For DNA-protein interaction studies	In vitro	Cancer / Male Reproduction/Neurobiology
Comet Assay -For DNA damage	In vitro	Cancer, Male reproduction
Transcription assay	In vitro	Cancer, Male reproduction
Clonogenic assay	In vitro	Cancer
Proteasome inhibition assay –For screening of proteasome inhibitors	In vitro	Cancer / Male Reproduction
Mammalian two hybrid assay- Cellular function	In vitro	Cancer / Male Reproduction
Flowcytometric TUNEL assay-DNA damage, apoptosis	In vitro	Cancer / Male Reproduction
PMN Phagocytosis assay- For screening of Phagocytosis	In vitro	Cancer / Male Reproduction
Flurometry based autophagy assay- For screening of Autophagy	In vitro	Cancer / Male Reproduction
Middle cerebral artery occlusion- For Screening of neuroprotective activity	In vitro	Neurobiology
Luciferase reporter assay- For evaluation of Transcriptional activity	In vitro	Cancer / Male Reproduction/Neurobiology
Neonatal SD rats for calvarial osteoblast cell isolation. -Use for assessing alkaline phosphatase activity as a measure of osteoblast differentiation and alizarin staining for osteoblast mineralization	In vitro	Osteoporosis/ Bone diseases
Peak bone mass measurements- Rats administered with compound showing promising in vitro activity. Treatment for one month, autopsied and bones and serum used for evaluating bone formation and resorption parameters.	In vitro	Osteoporosis/ Bone diseases
Adult SD osteopenic rat model. -Rats ovariectomized and left for a period of three months to develop osteopenia. Following this, osteopenic rats administered compound for three months, autopsied and bones and serum used for evaluating bone formation and resorption parameters	In vitro	Osteoporosis/ Bone diseases
Adult Ovariectomized Balb/c mice model. Mice ovariectomized and administered compound for one month, autopsied and bones and serum used for evaluating bone formation and resorption parameters	In vitro	Osteoporosis/ Bone diseases
Bone marrow culture from adult SD rats-For osteogenic differentiation	Ex vivo	Osteoporosis/ Bone diseases
Bone marrow culture from female Balb/c mice-For osteoclast differentiation	Ex vivo	Osteoporosis/ Bone diseases

* Minimum Quantity of the compound required, running cost of the assay and time required for the assay shall be communicated on request