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Dr. D. Srinivasa Reddy, PhD

Director, CSIR-CDRI

Dr. Srinivasa Reddy has more than 20 years of research experience in the synthesis of natural products/medicinal chemistry/drug discovery. Dr. Reddy is best known for his application oriented organic synthesis towards human wellbeing. He is also known for the application of “Silicon-switch approach” in medicinal chemistry. In addition, the work carried out by his group on crop protection is worth highlighting. He is an author of ~120 publications and an inventor in ~35 patents.

• Accomplished total synthesis of ~50 natural products of biological importance.

• One of the molecules (Licogliflozin) discovered by his team in industry is currently in human clinical trials (Phase-II), where he was a project leader.

• Has experience in coordinating multi-disciplinary teams as a PL.

• Acquired skills in designing novel small molecules and lead optimization.

• Experienced in planning and execution of projects (Govt. and Industry).

• Discovered an anti-diabetic lead molecule (along with Shantani Pvt Ltd, Pune).

• Out-licensed patent/technology (two nos.) developed by team at CSIR-NCL

• Identified Silinezolid with high brain:plasma ratio with a potential to treat brain infections.

• Identified of an antibiotic lead compound for treating food infections.

• Identified novel Insect Repellents – Further work is in progress.

• Developed a method to access enantiopure pheromones towards crop protection.

• Identified of novel Cladologs towards potent anti-malarial drug discovery.

Dr. Reddy received several national and international recognitions including the prestigious Shanti Swarup Bhatnagar Award (SSB) in Chemical Sciences and J. C. Bose National Fellowship by DST-SERB, Govt of India. He is also an editor of Bioorganic & Medicinal Chemistry Letters (BMCL), an Elsevier journal.

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