Asif Ali, Ph.D.
Principal Scientist, Division of Medicinal and Process Chemistry
Discovery, isolation and characterization of secondary metabolite
from Indian medicinal plants/microbes/marine organism.
Structural diversity of hit natural products for the
optimization of lead to achieve the new biological
knowledge.
RESEARCH INTEREST
➤ Isolation and structure elucidation of Natural Products from terrestrial plants, endophytic microbes and marine organisms including synthesis and bioactivity testing.
➤ Synthesis and synthetic modification of natural products for structure-activity studies.
➤ Diversity orientated synthesis of the hit molecule: Potent bioactive metabolite leads to chemical modification to enhance the biological function against cancer and neurological disorder.
➤ Detailed studies of extracts/ molecules against biological targets for cancer and neurological disorder.
➤ Synthesis of chiral compounds for use as chiral auxiliaries and chiral reagents.
➤ Develop the Novel glycosylation methods and their application in the synthesis of cell surface carbohydrates and glycolipids for potential immunogen.
➤ Structural diversity of crude extract using chemical engineering as a tool for the transformation of a diverse class of molecules against biological targets for cancer and neurological disorder to achieve new biological knowledge.