CSIR-CDRI Lucknow

Toxicity & Safety (GLP certified)

CDRI provides a comprehensive suite of GLP-compliant toxicology studies for NCEs and Phytopharmaceuticals. Their services encompass a wide array of preclinical toxicology assessments, ensuring rigorous evaluation in compliance with global regulatory standards. With years of experience and deep expertise, CDRI excels in delivering reliable and high-quality toxicology data, supporting the safety and efficacy of pharmaceutical and biotechnological products.

NGCMA Certified GLP Testing Facility

Toxicity Studies

1. Acute toxicity study in rodents by different routes

2. 28/90/180-day repeat dose toxicity study in rodents, rabbits, and monkeys

3. Histology of forty organs in rodents, rabbits, and monkeys

Reproductive and Developmental Toxicology Studies

1. Male fertility in rodents

2. Female fertility in rodents

3. Teratology in rodents

Safety Pharmacology Studies

1. Cardiovascular System (CVS) and Safety Studies.

2. Central Nervous System (CNS)

3. Respiratory System Safety Studies.

Genotoxicity Studies

1. AMES assay (Salmonella typhimurium)

2. In vitro Chromosomal aberration assay

3. In vitro micronucleus assay

4. In vivo Chromosomal aberration assay

5. In vivo micronucleus assay

hERG Liability Studies (GLP Compliant)

1. Determination of hERG liabity using manual patch clamp assays.