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Musculoskeletal Health and Disorders

Our efforts focus on developing innovative treatments for bone disorders and muscle atrophy, validating traditional remedies, studying disease biology, and creating new animal models. We leverage our expertise in drug design, repurposing, and mechanism investigation to achieve these goals.

Area Co-Ordinators

Divya  Singh

Kishor  Mohanan

Goals

  • ● Develop novel agents for bone-related disorders and skeletal muscle atrophy.
  • ● Scientific validation of traditional remedies.
  • ● Investigate disease biology, identify unique targets and pathways for future interventions.
  • ● Develop new animal models for disease pathogenesis and PK/PD studies.

Core Competencies and Activities

  • ● Design, synthesize, and bio-evaluate novel molecules/natural product isolates for new lead generation and managing osteoporosis/bone-related disorders.
  • ● Therapeutic repurposing of approved drugs.
  • ● Investigate mechanism of action of promising agents.

Team Members

  • Sanjay   Batra
  • Jimut K Ghosh
  • Atul  Goel
  • Narender  Tadigoppula
  • Prabhat R Mishra
  • Sanjeev  Kanojiya
  • Ritu  Trivedi
  • Koneni V Sashidhara
  • Naibedya  Chattopadhyay
  • Arun K Trivedi
  • Rajender  Singh
  • Sabyasachi   Sanyal
  • Jiaur R Gayen
  • Nilanjana  Majumdar