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Parasitic Infections

We focus on uncovering the molecular and biochemical mechanisms of diseases caused by parasites and to identify novel bioactive compounds to combat these diseases.

Area Co-Ordinators

Sanjay Batra

Saman Habib

Goals

  • ● Development of vaccines, new drugs/drug combinations and delivery systems.
  • ● Investigation of disease biology, host-pathogen interactions and immune evasion for potential interventions.
  • ● Development of recombinant bacterial strains and new animal models for exploring disease pathogenesis and PK/PD studies..

Core Competencies and Activities

  • ● Design, synthesis and bio-evaluation of novel molecules/natural products.
  • ● Plasmodium cynomolgi-rhesus macaque model for evaluation of advanced leads.
  • ● Mosquito rearing facility for investigating phenotypic effects of genetically manipulated parasites.
  • ● Molecular and structural approaches for decoding mechanisms of distinct metabolic and regulatory pathways.
  • ● Fluorescence-based membrane permeabilization approaches.

Team Members

  • Gautam Panda
  • Amogh A Sahasrabuddhe
  • Mohammad I Siddiqi
  • Prem P Yadav
  • Koneni V Sashidhara
  • J Venkatesh Pratap
  • Mrigank Srivastava
  • Namrata Rastogi
  • Kishor Mohanan
  • Pintu K Mandal
  • Satish Mishra
  • Niti Kumar
  • Ajay K Srivastava
  • Bidyut Purkait
  • Damodara R N
  • Ramesh Chintakunta
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