Vision and Goal:

- To carry out world class research on virus pathogenesis with emphasis on clinical applications to meet National priorities for tackling viral diseases with pandemic potential.
- Development of drug repurposing platforms for quickly countering emerging viral threats and specific chemical libraries using medicinal chemistry and acquisition approaches.
- Development of platform technologies for early detection of viral diseases, and safe and cost-effective vaccines.
- Research and development of oncolytic viruses targeting triple negative breast cancer.
- Therapeutic discovery applications for alleviating nationally important veterinary viral diseases in collaboration with other National institutes.

Core Competencies and Activities

- Virus culture facility for Japanese encephalitis, Dengue, SARS-Cov2, oncolytic viruses and other viruses important for the Nation.
- BSL-3 facilities for in vitro and in vivo assays and model systems.
- Therapeutics discovery and implementation of cutting-edge in vitro and in vivo assays.
- Compound libraries consisting of approved drugs, Phytopharmaceuticals and non-toxic compounds with platform assays for quick repurposing against emerging viruses with pandemic potential.
- Multi-institute collaborations with diverse institutes consisting of Medicinal chemists, Virologists, Structural Biologists, Artificial intelligence, Chemical biologists, Safety and toxicology,Clinicians and Veterinarians, to carry out the research and translational activities.
- Developing ex vivo models of viral infection using human organoid cultures.
- Addressing questions regarding cell trafficking, cytokine control of infection, and cell-mediated immunity.