CDRI-Online Recruitment

List of Posts/पदों की सूची

Post Code	Area	Post Name	No of Post	Age Limit & Pay Band	Essential Educational Qualifications & Experience	Desirable qualification & Experience	Job requirement / Specification
001	Pharmaceutics and Pharmacokineti cs Division	Scientist	2 (1 OBC & 1 UR)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (Submitted) in the area of Pharmaceutical Sciences or equivalent.	Experience in the area of development and validation of HPLC and LC-MS/MS analytical and bioanalytical methods of APIs/formulations, Pharmacokinetic studies, metabolite identification and bio-distribution; PK/PD modelling for early drug discovery and development program, animal handling and thorough understanding of drug delivery. Master level course work in formulation development and Pharmacokinetics achieving proficiency in drug delivery, HPLC and LC-MS/MS analytical/bioanalytical methods and PK studies. A record of peer reviewed publications in SCI journals and/or patents demonstrating expertise in Pharmacokinetic studies.	The candidate will be responsible for development and validation of analytical and bioanalytical methods for APIs/ formulations from blood/plasma/serum/tissue samples, design and conduct of pharmaco-kinetics studies in rodents and non-human primates, pharmacokinetic modeling, metabolite identification, in vitro ADME studies, development of formulations and delivery systems in line with CDRI mandate and provide support for drug discovery projects.
002	Medicinal Chemistry	Scientist	5 (1 OBC & 2 UR & 1 ST & 1 EWS)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (Submitted) in the area of Chemical Sciences/ Medicinal Chemistry or equivalent	Experience in synthetic methodologies designing of chemical compounds for biological activity against disease-prioritized targets and their synthesis. Expertise in the use of in silico modeling tools for hypothesis-driven design of novel compounds and exploration of structure-activity relationships. Experience in structural determination using spectroscopic techniques as well as knowledge of related purification methods. A record of publications and/or patent applications demonstrating proficiency in synthetic chemistry/ medicinal chemistry.	Design and synthesize novel chemical compounds to optimize potency, selectivity, pharmacokinepharmacokinetics, and in vivo efficacy. Analyze the data sets to generate structure-activity relationships within the chemical library. Interface with biological and pharmacological collaborators in the testing and development of interesting compounds. The candidate is expected to take up teaching assignments in Pre-PhD courses too. Candidates are expected to write R&D projects in the respective areas for extramural funding.
003	Medicinal Chemistry	Scientist	1 (1 UR)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	PhD (submitted) In the area of Organic Chemistry/ Medicinal Chemistry or equivalent.	Experience in methods of synthetic and medicinal chemistry. Experience in designing and synthesizing PROTACs for therapeutic applications. A record of publications and/or patent applications demonstrating proficiency in PROTAC design and synthesis.	Apply state-of-the-art Med Chem approaches to synthesize PROTAC molecules towards a broad spectrum of diseases, including immune-oncology, inflammation, and neurodegeneration such as Alzheimer’s and Parkinson’s diseases. The candidate is expected to take up teaching assignments in Pre-PhD courses too. Candidates are expected to write R&D projects in the respective areas for extramural funding.
004	Medicinal Chemistry	Scientist	1 (1 UR)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (Submitted) in the area of Chemical Sciences/ Medicinal Chemistry or equivalent.	Experience in the area of ADC development, generation, optimization and characterization of antibody-drug conjugates. Experience in purification using liquid chromatography methods. A record of publications and/or patent applications demonstrating proficiency in ADC development.	Design small molecules for lead discovery and optimization with a focus on intermediates for antibody-drug conjugates. Create and perform conjugations between proteins and small molecules. Carry out the antibody and conjugate validation via various functional tests. Carry out biophysical characterization of proteins and conjugates . The candidate is expected to take up teaching ssignments in Pre-PhD courses. Candidates are expected to write R&D projects in the respective areas for extramural funding.
005	Computational Chemistry	Scientist	2 (1 UR & 1 SC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (Submitted) In the area of computational Chemistry/Molecular Biophysics or related area with focus on Chemi-informatics/pharmaco-informatics or equivalent.	Experience in Computational chemistry methodologies (structure- and ligand-based approaches & virtual screening, reaction modeling and computer assisted synthesis planning), AI & ML usage in drug discovery space. Experience in molecular dynamic simulations, QSAR and toxicity predictions, free energy calculation, force field development, density functional theory, quantum chemistry, and hybrid QM/MM simulation. Experience in Chem-Informatics toolkits and packages (e.g. Schrodinger, Discovery Studio, ChemAxon etc), Proficiency in working in a Unix/Linux environment. Competency Experience in programming, code development, and software architecture. A record of publications and/or patent applications demonstrating proficiency in Computational Chemistry.	Initiate development of new models, algorithms and methodologies to align with the latest developments in the field. Collaborate with colleagues in medicinal chemistry and other teams for providing scientific knowledge obtained through molecular modelling, supporting small molecule drug discovery. Identify areas of application for AI in Chemistry and related Lifesciences, and develop novel algorithms to drive data-driven drug discovery.
006	Microbial Infection	Scientist	1 (1 OBC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (Submitted) In the area of Microbiology/Biotechnology/Life Sciences	1.Ph. D. with M. Sc. In Microbiology/Biotechnology/Life Sciences 2. Postdoctoral experience 3.Experience of working with clinical/resistant microbial strains in BSL-2 and/or BSL-3 facility. 4. Experience in animal models, molecular microbiology, microbial genetics, genome/RNA sequencing, Drug screening, mechanistic studies and data analysis as evidenced by publications in peer reviewed SCI journals	The candidate is expected to carry out research in the area of Microbial Infections employing in vitro systems and animal models (using BSL-3/BSL-2 facilities) to understand disease pathogenesis. The candidate is expected to carry out research in the area of Microbial Infections employing in vitro systems and animal models (using BSL-3/BSL-2 facilities) to understand disease pathogenesis. The focus will be on ESKAPE pathogens or Mycobacterium. The candidate will also be expected to run target based or mechanism driven drug discovery programs for the identification of antimicrobial hits and leads.
007	Animal Genetics and Breeding	Scientist	1 (1 OBC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	M.V.Sc in the area of animal genetics and animal breeding.	PhD in the area of animal genetics and animal breeding. Experience in breeding and maintenance of rodent / non-rodent colonies / transgenic animals /embryo cryopreservation and rederivation techniques.	The incumbent is expected to plan and execute the breeding programme of rodents and non-rodents. The incumbent should also look after the daily management of the laboratory animal facility, participate in health monitoring of animals and experimentation
008	Reproductive Biology (Male Reproduction)	Scientist	1 (1 UR)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	MD/MVSc. In Life Science or Ph. D. (submitted) in Life Science	Experience in unraveling the molecular mechanisms regulating male / female reproductive biology. Molecular processes underpinning regulatory signaling mechanisms in spermatogenesis and contraception. A record of publications and/or patent applications demonstrating proficiency in the field.	Planning and execution of basic and translational research projects in the area of male reproductive biology including cell biology, cell signaling, contraception and development & validation of novel in vitro and animal models in the area.
009	Reproductive Biology (Female Reproduction)	Scientist	1 (1 OBC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	MD/MVSc. In Life Science or Ph.D. (submitted) in Life Science	Experience in areas of Ovarian biology (Ovulation, Fertilization, Endocrinology, etc.), Endometrial biology (Preimplantation and post-implantation biology), placental biology: (placental development), Female contraception and exposure to transgenic mice handling. Experience in probing molecular signaling pathways and cellular interactions relevant to female reproductive biology. A record of publications and/or patent applications demonstrating proficiency in the field.	Planning and execution of basic and translational research projects in the area of female reproductive biology including cell biology, signaling, contraception and development & validation of novel in vitro and animal models in the area.
010	Toxicology and Experimental Medicine	Scientist	2 (1 UR & 1 SC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (submitted) in the area of Toxicology/ Biochemistry/ Zoology) OR MD in Pathology/ Pharmacology/ Toxicology OR MVSc. In Pharmacology & Toxicology	Experience in toxicity evaluation protocols required for development of NCEs and biologicals, handling of rodents and other laboratory animals. A record of publications in peer-reviewed SCI journals demonstrating proficiency in drug development/toxicology.	Planning and execution of preclinical studies in rodents and non-human primates in a GLP Environment and supporting drug discovery projects.
011	Project Management	Scientist	1 (1 SC)	Age Limit: 32 Pay Matrix Level: 11 as per 7th CPC	Ph.D. (submitted) in the area of Life Sciences or Chemical Sciences or Pharmaceutical Sciences or equivalent	Project Management or Research Management Fellowship or experience in Project/R&D/ Research Management in the CSIR/ DBT/DST/DRDO Organizations/ Institutes/ Pharma Industries	* Coordination of planning of R&D Programs. * Monitoring, risk management, and reporting of institutional, national and international projects/ Programs being implemented ; * Preparation of institutional reports, publications, and technical documents; Pre-Grant and Post-Grant Management as per standard practices/guidelines of national and international funding agencies Any tasks assigned in the area of S&T Management.