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Research Interest


Therapeutic peptides have several advantages over organic molecules or antibodies: as they have a high target specificity and selectivity and have low toxicity. In this regard we are interested in peptides and peptidomimetics of their therapeutic and diagnostic applications.


1) Design and Synthesis of Smac Mimetics as a Potential Anticancer Agents

2) Developing drug targets for BCL-XL protein

3) Total Synthesis of Bioactive Natural Peptide Scaffolds


4) Methodology Development for the Macrolactamization of Bioactive Scaffolds


5) Total Synthesis and Site Selective Labelling of Natural Proteins


6) Development of Potential Non-haemolytic Antibiotics: We also plan to explore the cell permeability and antimicrobial activity of cyclic tetrapeptides and helical peptides on drug-resistant pathogens. Indeed, tetracyclic peptides and helical oligomer scaffolds cause this unique high permeability in cells.


5) Total Synthesis and Site Selective Labelling of Natural Proteins

Development of new methodologies for bioactive molecules



New approaches for privileged heterocyclic scaffolds based on transition metal catalysis

Target based approaches for bioactive molecules