SMEDDS are for oral treatment of MDR P. falciparum.
Oral formulation containing three anti-malarial drugs alpha/beta-arteether, sulfadoxine and pyrimethamine.
No formulation of alpha,beta-arteether is so far available for oral administration.
Prepared SMEDDS have the blend of drug, oil and surfactants. These surfactants were known to increase the permeability by disturbing the cell membrane and thus enhance the absorption of poorly soluble drugs.
Patent Filed: Novel combination kit for treatment of malaria. Tripathi Renu, Mishra Prabhat Ranjan, Dwivedi Pankaj, Dwivedi Hemlata, Singh Sunil Kumar, Puri Sunil Kumar, Dwivedi Anil Kumar. Indian Patent Application No: 1983/DEL/2014.