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Cardiovascular, Central Nervous System & Other Disorders

  • The research activities in “CNS-CVS and related disorders” includes, design, synthesis and development of new drugs to treat pathologies of:

    • image01     Cardiovascular (hypertension, dyslipidemia, atherosclerosis, stroke, and thrombosis)

    • image01     Central Nervous System (Anxiety, depression, Alzheimers, and Parkinson’s diseases)

    • image01     Other related disorders (metabolic disorders and inflammation).

  • Development of suitable animal models, and in vitro tests (isolated cells, cell lines and enzymes assays) to evaluate synthetic compounds, plant and marine extracts or fractions, are the activities of the project in quest of new target based drugs. Researches to delineate the molecular mechanisms of these pathologies are being carried out so as identify suitable targets for drug discovery, as well as to analyze the possible mechanism(s) of action of the candidate drugs.

    Under this project several drugs/formulations had been developed and licensed to various pharmaceutical companies. We are open to collaborations both national & international.

    Interactive teams of biologists and chemists from the Divisions of Pharmacology, Medicinal & Process Chemistry, Toxicology, Biochemistry, Pharmacokinetics, Pharmaceutics and Clinical & Experimental Medicine work synergistically under the project. In addition to intramural funding, the project is supported by Department of Science & Technology, Department of Biotechnology, Indian Council of Medical Research, Department of AYUSH, and Ministry of Earth Sciences.