Research Interests

I direct the Centre for Research in Anabolic Skeletal Targets in Health and Illness (ASTHI) funded by CSIR since 2012. Centre ASTHI, dedicated to research in bone biology and metabolic bone disease, is first and only-of-its-kind in the country. The overall goal of the centre is to foster interdisciplinary and collaborative work that would lead to a deeper understanding of skeletal biology, in a way that would lead to new ways of diagnosing and treating skeletal diseases.Broad objectives of the centre are;
i) application of novel approaches to understand the processes underlying biomineralization of bone tissue, which is translatable to therapeutics in future
ii) to understand the physiology of bone anabolism at modeling and remodeling stages using state-of-the-art genetic engineering in mice, which would provide a fresh paradigm in the understanding of the pathophysilogy of postmenopausal osteoporosis
iii) engineering a novel system for augmented deliverance of experimental therapeutics with bone anabolic effect

Collaborating institutions:

i. Indian Institute of Technology-Kanpur
ii. Indian Institute of Technology-Mumbai
iii. National Centre for Cell Sciences, Pune
iv. Sanjay Gandhi Post-graduate Institute of Medical Sciences, Lucknow
v. Centre of Bio-Medical Research, Lucknow
vi. National Dairy Research Institute, Karnal
vii. Kemxtree LLC, USA/Enem Nostrum, Mumbai
viii. Zydus Research Laboratory, Ahmedabad